In the hustle and bustle of thriving cities, people as well as goods rely on well-functioning transportation systems to timely arrive at their destinations. Likewise, the macromolecules within a living cell need to be organized spatially as well as temporally to maintain its complexity of biochemical reactions and interactions. This is accomplished by a highly organized and versatile protein machinery that shuttles intracellular cargoes to their different points of destinations. Just as a malfunction in the public transportation system obstructs public live, disfunctions in the cellular transportation system often cause severe defects and deseases.
In our group, we dissect the mechanisms of various intracellular transport processes at the molecular level.
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