Kinesin-2 from C. reinhardtii is an atypically fast and auto-inhibited motor that is activated by heterotrimerization for intraflagellar transport

Punam Sonar, Wiphu Youyen, Augustine Cleetus, Pattipong Wisanpitayakorn, Iman S. Mousavi, Willi L. Stepp, William O. Hancock, Erkan Tüzel, Zeynep Ökten

2020

Molecular Underpinnings of Cytoskeletal Crosstalk

Angela Oberhofer, Emanuel Reithmann, Peter Spieler, Willi L Stepp, Dennis Zimmermann, Bettina Schmid, Erwin Frey, Zeynep Ökten

Proc Natl Acad Sci 201917964

2020

Resolving kinesin stepping: one head at a time

Willi L. Stepp & Zeynep Ökten

Life science alliance 2 (5)

2019

Reconstitution reveals motor activation for intraflagellar transport

Mohamed A.A. Mohamed, Willi L. Stepp, Zeynep Ökten

Nature 557, 387–391

2018

Kinesin-2 motors adapt their stepping behaviour for processive transport on axonemes and microtubules

Willi L. Stepp, Georg Merck, Felix Mueller-Planitz, Zeynep Ökten

EMBO Rep 18, 1947–1956

2017

Myosin Va’s adaptor protein melanophilin enforces track selection on the microtubule and actin networks in vitro

Angela Oberhofer, Peter Spieler, Yuliya Rosenfeld, Willi L. Stepp, Augustine Cleetus, Alistair N. Hume, Felix Mueller-Planitz, and Zeynep Ökten

PNAS vol. 114 no. 24

2017

Torque generation of Kinesin motors is governed by the stability of the neck domain

M. Brunnbauer, R. Dombi, T. H. Ho, M. Schliwa, M. Rief, Z. Ökten

Molecular Cell 2, 147-58

2012

Diffusion of myosin V on microtubules: a fine-tuned interaction for which E-hooks are dispensable

D. Zimmermann, B. Abdel Motaal, L. Voith von Voithenberg, M. Schliwa, Z. Ökten

PLoS One 6(9):e25473

2011

How kinesin-2 forms a stalk

M. Vukajlovic, H. Dietz, M. Schliwa, Z. Ökten

Mol Biol Cell 22(22):4279-87

2011

The Lever Arm Effects a Mechanical Asymmetry of the Myosin-V-Actin Bond

J. C. M. Gebhardt, Z. Ökten, M. Rief

Biophysical Journal 98:277-281

2010

Regulation of a heterodimeric kinesin-2 through an unprocessive motor domain that is turned processive by its partner

M. Brunnbauer, F. Mueller-Planitz, S. Kösem, T. H. Ho, R. Dombi, J. C. M. Gebhardt, M. Rief, Z. Ökten

Proc Natl Acad Sci U S A 107:10460-10465

2010

Molecular motors: A step dissected

Z. Ökten, M. Schliwa

Nature 450(7170):625-6

2007

Single molecule high-resolution colocalization of Cy3 and Cy5 attached to macromolecules measures intramolecular distances through time

L. S. Churchman, Z. Ökten, R. S. Rock, J. F. Dawson, J. A. Spudich

Proc Natl Acad Sci U S A 102(5):1419-23

2005

Myosin VI walks hand-over-hand along actin

Z. Ökten, L. S. Churchman, R. S. Rock, J. A. Spudich

Nat Struct Mol Biol 11(9):884-7

2004

TUM | Munich | Germany