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The physiological cargo adaptor of kinesin-2 functions as an evolutionary conserved lockpick.

Cleetus A, Merck G, Mueller-Planitz F, Ökten Z.

PNAS vol. 119 no. 33


DYF-5/MAK-dependent phosphorylation promotes ciliary tubulin unloading.

Jiang X, Shao W, Chai Y, Huang J, Mohamed MAA, Ökten Z, Li W, Zhu Z, Ou G.

PNAS vol. 119 no. 34


Optimal sidestepping of intraflagellar transport kinesins regulates structure and function of sensory cilia.

Xie C, Li L, Li M, Shao W, Zuo Q, Huang X, Chen R, Li W, Brunnbauer M, Ökten Z, Chen L, Ou G.

EMBO J. vol. 39 no.12


Molecular Underpinnings of Cytoskeletal Crosstalk

Angela Oberhofer, Emanuel Reithmann, Peter Spieler, Willi L Stepp, Dennis Zimmermann, Bettina Schmid, Erwin Frey, Zeynep Ökten

Proc Natl Acad Sci 201917964


Kinesin-2 from C. reinhardtii is an atypically fast and auto-inhibited motor that is activated by heterotrimerization for intraflagellar transport

Punam Sonar, Wiphu Youyen, Augustine Cleetus, Pattipong Wisanpitayakorn, Iman S. Mousavi, Willi L. Stepp, William O. Hancock, Erkan Tüzel, Zeynep Ökten


Resolving kinesin stepping: one head at a time

Willi L. Stepp & Zeynep Ökten

Life science alliance 2 (5)


Reconstitution reveals motor activation for intraflagellar transport

Mohamed A.A. Mohamed, Willi L. Stepp, Zeynep Ökten

Nature 557, 387–391


Kinesin-2 motors adapt their stepping behaviour for processive transport on axonemes and microtubules

Willi L. Stepp, Georg Merck, Felix Mueller-Planitz, Zeynep Ökten

EMBO Rep 18, 1947–1956


Myosin Va’s adaptor protein melanophilin enforces track selection on the microtubule and actin networks in vitro

Angela Oberhofer, Peter Spieler, Yuliya Rosenfeld, Willi L. Stepp, Augustine Cleetus, Alistair N. Hume, Felix Mueller-Planitz, and Zeynep Ökten

PNAS vol. 114 no. 24


In vitro reconstitution of an mRNA-transport complex reveals mechanisms of assembly and motor activation.

Heym RG, Zimmermann D, Edelmann FT, Israel L, Ökten Z, Kovar DR, Niessing D.

J Cell Biol. vol. 203 no.6


A non-mitotic CENP-E homolog in Dictyostelium discoideum with slow motor activity

Kösem S, Ökten Z, Ho TH, Trommler G, Koonce MP, Samereier M, Müller-Taubenberger A.

Biochem Biophys Res Commun. vol. 431 no.3


Torque generation of Kinesin motors is governed by the stability of the neck domain

M. Brunnbauer, R. Dombi, T. H. Ho, M. Schliwa, M. Rief, Z. Ökten

Molecular Cell 2, 147-58


How kinesin-2 forms a stalk

M. Vukajlovic, H. Dietz, M. Schliwa, Z. Ökten

Mol Biol Cell 22(22):4279-87


Diffusion of myosin V on microtubules: a fine-tuned interaction for which E-hooks are dispensable

D. Zimmermann, B. Abdel Motaal, L. Voith von Voithenberg, M. Schliwa, Z. Ökten

PLoS One 6(9):e25473


Regulation of a heterodimeric kinesin-2 through an unprocessive motor domain that is turned processive by its partner

M. Brunnbauer, F. Mueller-Planitz, S. Kösem, T. H. Ho, R. Dombi, J. C. M. Gebhardt, M. Rief, Z. Ökten

Proc Natl Acad Sci U S A 107:10460-10465


The Lever Arm Effects a Mechanical Asymmetry of the Myosin-V-Actin Bond

J. C. M. Gebhardt, Z. Ökten, M. Rief

Biophysical Journal 98:277-281


Molecular motors: A step dissected

Z. Ökten, M. Schliwa

Nature 450(7170):625-6


Single molecule high-resolution colocalization of Cy3 and Cy5 attached to macromolecules measures intramolecular distances through time

L. S. Churchman, Z. Ökten, R. S. Rock, J. F. Dawson, J. A. Spudich

Proc Natl Acad Sci U S A 102(5):1419-23


Myosin VI walks hand-over-hand along actin

Z. Ökten, L. S. Churchman, R. S. Rock, J. A. Spudich

Nat Struct Mol Biol 11(9):884-7


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